<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Combescot,Charles</style></author><author><style face="normal" font="default" size="100%">Combescot-Lang,Catherine</style></author><author><style face="normal" font="default" size="100%">Nadon,Jacques de</style></author><author><style face="normal" font="default" size="100%">Remy-Kristensen,Arlette</style></author><author><style face="normal" font="default" size="100%">Richard-Lenoble,Dominique</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Interest and limits of tests to evaluate pediculicides efficacy</style></title><secondary-title><style face="normal" font="default" size="100%">Bulletin de L Academie Nationale de Medecine</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">drug</style></keyword><keyword><style  face="normal" font="default" size="100%">drugs</style></keyword><keyword><style  face="normal" font="default" size="100%">insecticide</style></keyword><keyword><style  face="normal" font="default" size="100%">lice</style></keyword><keyword><style  face="normal" font="default" size="100%">Pediculosis</style></keyword><keyword><style  face="normal" font="default" size="100%">resistance</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">1996</style></year><pub-dates><date><style  face="normal" font="default" size="100%">1996</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">180</style></volume><pages><style face="normal" font="default" size="100%">1315 - 1324</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">The obligation to prove pediculicides efficacy is relatively recent.  Two tests are required by the autorities to obtain registration, In  vitro test (with Pediculus humanus humanus) is the first step to  evaluate the efficacy of new molecules. It must be followed by  bio-clinical tests (with infested children by Pediculus humanus  capitis). For those tests the autors advise to respect the ''three  units rule'' : unit of time (no more than 2 days for the test), unit of  place (same environment) and unit of action (only one team to apply and  evaluate products). This type of tests is possible only in countries  with high infestation (at least 60 % of prevalence). A third test is  consequently advised, the ex vivo test using Pediculus humanus capitis  obtained from infested children in France. This test can be useful also  to re-evaluate current products in the light of increased resistance or  decreased sensitivity of the lice. Finally some other tests can be  advised to prove some other activities like remanence or repellent  properties or to estimate lice resistance.</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue></record></records></xml>