@article {47904,
	title = {Insights into social insects from the genome of the honeybee Apis mellifera},
	journal = {Nature},
	volume = {443},
	year = {2006},
	month = {2006},
	pages = {931 - 949},
	abstract = {<p>Here we report the genome sequence of the honeybee Apis mellifera, a key model for social behaviour and essential to global ecology through pollination. Compared with other sequenced insect genomes, the A. mellifera genome has high A1T and CpG contents, lacks major transposon families, evolves more slowly, and is more similar to vertebrates for circadian rhythm, RNA interference and DNAmethylation genes, among others. Furthermore, A. mellifera has fewer genes for innate immunity, detoxification enzymes, cuticle-forming proteins and gustatory receptors, more genes for odorant receptors, and novel genes for nectar and pollen utilization, consistent with its ecology and social organization. Compared to Drosophila, genes in early developmental pathways differ in Apis, whereas similarities exist for functions that differ markedly, such as sex determination, brain function and behaviour. Population genetics suggests a novel African origin for the species A. mellifera and insights into whether Africanized bees spread throughout the New World via hybridization or displacement.</p>
},
	keywords = {genome, Phthiraptera, Phylogeny},
	doi = {10.1038/nature05260},
	url = {http://phthiraptera.info/sites/phthiraptera.info/files/47904.pdf},
	author = {Weinstock,George M. and Robinson,Gene E. and Gibbs,Richard A. and et al}
}
