@article {46610,
	title = {The avermectins: A new family of antiparasitic agents},
	journal = {Journal of the South African Veterinary Association},
	volume = {53},
	year = {1982},
	note = {LR: 20031114; JID: 7503122; 0 (Anthelmintics); 0 (Antinematodal Agents); 0 (Lactones); 65195-55-3 (avermectin B(1)a); 65195-57-5 (avermectin B2a); 70288-86-7 (Ivermectin); 73989-17-0 (avermectin); RF: 34; ppublish},
	month = {1982},
	pages = {87 - 90},
	address = {SOUTH AFRICA},
	abstract = {The avermectins are macrocyclic lactones produced by fermentation of the soil micro-organism Streptomyces avermitilis. They show activity against a broad range of nematodes and arthropod parasites of domestic animals at dose rates of 300 microgram/kg or less. Unlike the macrolide or polyene antibiotics, they lack significant antibacterial or antifungal activity. By oral or parenteral administration, avermectins are active against gastrointestinal nematodes and lungworms, and important ectoparasites such as lice, mange mites, ticks and larval stages of flies. They show excellent activity against parasites resistant to existing anthelmintics or ectoparasiticides. The avermectins appear to cause paralysis of nematodes and arthropods by opening gamma-aminobutyric acid-mediated chloride channels at the neuromuscular junction.},
	keywords = {animals, Anoplura, anthelmintic, Antinematodal Agents/therapeutic use, cattle, Cattle Diseases, Dog Diseases, Horse Diseases, horses, Ivermectin/analogs \& derivatives, Lactones, Mite Infestations/drug therapy/veterinary, Nematode Infections/veterinary, sheep, Sheep Diseases/drug therapy, Swine, Swine Diseases/drug therapy, Tick Infestations/drug therapy/veterinary},
	isbn = {1019-9128},
	author = {Hotson,I. K.}
}
@article {46577,
	title = {The efficacy of ivermectin against helminth and arthropod parasites of impala},
	journal = {Journal of the South African Veterinary Association},
	volume = {54},
	year = {1983},
	note = {LR: 20031114; JID: 7503122; 0 (Anthelmintics); 0 (Lactones); 70288-86-7 (Ivermectin); ppublish},
	month = {1983},
	pages = {251 - 253},
	address = {SOUTH AFRICA},
	abstract = {<p>The efficacy of ivermectin, injected subcutaneously at a dosage rate of 200 mcg/kg live mass, was determined against nematodes, ixodid ticks and lice infestations acquired by free-living impala, Aepyceros melampus, in the Kruger National Park. Although the parasite burdens of the untreated control animals varied considerably, ivermectin appeared to be highly effective against 7 nematode species and effective against 3 others. Of the 4 tick species recovered, only Boophilus decoloratus appeared to have been affected. In the case of the lice infestations, ivermectin was highly effective against 3 species of Linognathus, but ineffective against the 2 Damalinia species present.</p>
},
	keywords = {animals, Antelopes/parasitology, anthelmintic, Artiodactyla/parasitology, Injections, Ivermectin, Lactones, lice, Nematode Infections/drug therapy/veterinary, Tick Infestations/drug therapy/veterinary},
	isbn = {1019-9128},
	url = {https://www.researchgate.net/publication/16507762_The_efficacy_of_ivermectin_against_helminth_and_arthropod_parasites_of_impala},
	author = {Horak,Ivan G. and Boomker,J. and Kingsley,S. A. and De Vos,V.}
}
@article {46560,
	title = {Ivermectin as an antiparasitic agent in cattle},
	journal = {Modern veterinary practice},
	volume = {65},
	year = {1984},
	note = {LR: 20031114; JID: 7802904; 0 (Anthelmintics); 0 (Insecticides); 0 (Lactones); 70288-86-7 (Ivermectin); ppublish},
	month = {1984},
	pages = {669 - 672},
	address = {UNITED STATES},
	abstract = {In experimental trials on cattle, ivermectin given SC at 200 micrograms/kg had 95\% or better efficacy against adult and immature GI and pulmonary nematodes, including inhibited fourth-stage larvae of Ostertagia ostertagi. Studies of efficacy against ectoparasites revealed nearly 100\% efficacy against sucking lice, psoroptic and sarcoptic mange mites and cattle grubs. Safety trials revealed no adverse effects with the recommended dosage, including bulls and pregnant cows. A few grub-infested cattle died from acute esophagitis associated with a host-parasite reaction after ivermectin injection.},
	keywords = {animals, Anoplura, anthelmintic, cattle, Cattle Diseases, Diptera, ectoparasite, insecticide, Ivermectin, Lactones, Mites/isolation \& purification, Nematode Infections/drug therapy/veterinary},
	isbn = {0362-8140},
	author = {Leaning,W. H.}
}
@article {46544,
	title = {Efficacy of ivermectin against the sucking louse Solenopotes capillatus},
	journal = {Veterinary Record},
	volume = {116},
	year = {1985},
	month = {1985},
	pages = {267},
	keywords = {animals, Anoplura, cattle, Cattle Diseases, Drug Evaluation, insecticide, Ivermectin, Lactones, Lice Infestations/drug therapy/veterinary, Random Allocation, Streptomycin/therapeutic use},
	author = {Barth,D. and Preston,J. M.}
}
