02161nas a2200217   4500008004100000022001300041245009500054210006900149260001600218300001200234490000800246520149300254653001701747653001501764653002101779653001501800653001401815100002301829700002401852856006701876       2017                        eng d  a0022191000aHype or opportunity? Using microbial symbionts in novel strategies for insect pest control0 aHype or opportunity Using microbial symbionts in novel strategie  cJan-11-2017  a10 - 170 v1033 a<p>All insects, including pest species, are colonized by microorganisms, variously located in the gut and within insect tissues. Manipulation of these microbial partners can reduce the pest status of insects, either by modifying insect traits (e.g. altering the host range or tolerance of abiotic conditions, reducing insect competence to vector disease agents) or by reducing fitness. Strategies utilizing heterologous microorganisms (i.e. derived from different insect species) and genetically-modified microbial symbionts are under development, particularly in relation to insect vectors of human disease agents. There is also the potential to target microorganisms absolutely required by the insect, resulting in insect mortality or suppression of insect growth or fecundity. This latter approach is particularly valuable for insect pests that depend on nutrients from symbiotic microorganisms to supplement their nutritionally-inadequate diet, e.g. insects feeding through the life cycle on vertebrate blood (cimicid bugs, anopluran lice, tsetse flies), plant sap (whiteflies, aphids, psyllids, planthoppers, leafhoppers/sharpshooters) and sound wood (various xylophagous beetles and some termites). Further research will facilitate implementation of these novel insect pest control strategies, particularly to ensure specificity of control agents to the pest insect without dissemination of bio-active compounds, novel microorganisms or their genes into the wider environment.</p>
10aBacteriocyte10aMicrobiome10aParatransgenesis10aSymbiocide10asymbiosis1 aArora, Arinder, K.1 aDouglas, Angela, E.  uhttps://linkinghub.elsevier.com/retrieve/pii/S0022191017303463