02842nas a2200277   4500008004100000245015900041210006900200260000900269520188400278653001302162653001002175653001502185653001602200653001702216653001602233653001602249653001102265100001802276700002602294700001602320700002302336700002002359700002102379700002302400856014102423       2006                        eng d00aTherapeutic and persistent efficacy of spinosad applied as a pour-on or a topical spray against natural infestations of chewing and sucking lice on cattle0 aTherapeutic and persistent efficacy of spinosad applied as a pou  c20063 aStudies were conducted in Wisconsin and Illinois, USA, to assess and compare the therapeutic and persistent efficacy of spinosad when applied as either a pour-on or topical spray and compared with cyfluthrin pour-on and coumaphos topical spray for controlling natural infestations of chewing (Bovicola bovis) and sucking (Linognathus vituli, Solenopotes capillatus and Haematopinus eurysternus) lice on cattle. Thirty-five animals at each trial site were blocked according to pre-treatment lice counts and randomly allocated to one of five treatment groups: single treatments of spinosad (25g/L), diluted with water to 0.04% active ingredient and applied as a whole-body topical spray; spinosad (25g/L) applied as a neat pour-on at 2mg/kg body weight; Co-Ral((R)) Emulsifiable Livestock Insecticide (5.8% coumaphos), diluted to 0.03% active ingredient and applied as a whole-body topical spray; CyLence((R)) Pour-on Insecticide (1% cyfluthrin), applied as a neat pour-on at the manufacturer's recommended use rate for lice; and untreated control. Both spinosad treatments and cyfluthrin provided >/=96% control of B. bovis for up to 7 weeks, whereas the efficacy of coumaphos dropped to <90% after week 5 at one site. Spinosad spray had the best therapeutic and residual control of all treatments against L. vituli, >/=98% for at least 5 weeks at both sites, compared with 3 weeks for coumaphos at one site. Spinosad and coumaphos sprays provided 100% control of S. capillatus for at least 8 weeks compared with >/=97% control for spinosad and cyfluthrin pour-on treatments over the same interval. While H. eurysternus burden was low and limited to one study site, all four treatments provided 100% control for at least 6 weeks. These studies showed that topically applied spinosad provided a high degree of therapeutic and residual control against both sucking and chewing lice.10aBovicola10abovis10acapillatus10aeurysternus10aHaematopinus10aLinognathus10aSolenopotes10avituli1 aWhite, Hunter1 aHutchens, Douglas, E.1 aJones, Carl1 aFirkins, Larry, D.1 aPaul, Allan, J.1 aSmith, Larry, L.1 aSnyder, Daniel, E.  uhttps://phthiraptera.myspecies.info/content/therapeutic-and-persistent-efficacy-spinosad-applied-pour-or-topical-spray-against-natural-i