TY - JOUR T1 - Arbovirological survey in Silica plateau area, Roznava District, Czechoslovakia JF - Journal of Hygiene, Epidemiology, Microbiology, and Immunology Y1 - 1986 A1 - Hubalek,Z. A1 - Černý,Vladimír A1 - Mittermayer,T. A1 - Kilik,J. A1 - Halouzka,J. A1 - Juricova,Z. A1 - Kuhn,I. A1 - Bardos,V. SP - 87 EP - 98 KW - adolescent KW - adult KW - Age Factors KW - Aged KW - animals KW - Antibodies, Viral/analysis KW - Arboviruses/immunology/isolation & purification KW - cattle KW - child KW - Czechoslovakia KW - goats KW - Hemagglutination KW - humans KW - Lice/microbiology KW - mice KW - Mice, Inbred ICR KW - Middle Aged KW - Neutralization Tests KW - sheep KW - Ticks/microbiology AB -

The serosurveys conducted in the Silica plateau area of the Slovak karst region revealed the presence of specific neutralizing antibody against tick-borne encephalitis (TBE) virus in 18% of local inhabitants (33 examined, mostly goats and sheep farmers), 54% of goats (26 examined), 18% of sheep (120 examined) and 13% of cattle (60 examined), against Lipovnik (LIP) virus in 30% of inhabitants, 88% of goats, 55% of sheep and 45% of cattle, and against Bhanja (BHA) virus in 27% of inhabitants, 46% of goats, 29% of sheep and 23% of cattle. The results of hemagglutination-inhibition tests with TBE and BHA antigens were analogous. A detailed analysis of these serologic data points to a recent enhancement of the circulation of LIP and BHA viruses and to a very low TBE virus activity in this natural focus of arboviral infections. The immunological surveys of the 32 former "Roznava disease" patients, conducted 25 years after an extensive epidemic of a TBE virus infection that originated in Roznava in 1951, revealed the presence of neutralizing (and also hemagglutination-inhibiting) antibodies against TBE virus in as many as 78% of cases. Antibodies against LIP and BHA viruses were also detectable in the sera of 16% and 9%, respectively, of these individuals. Populations of the ectoparasites examined for the presence of arbovirus comprised 231 Ixodes ricinus, 806 Dermacentor marginatus and 204 Haemaphysalis punctata ticks and 117 specimens of the louse-flies Melophagus ovinus. Two strains of arbivirus that were antigenically related to Lipovnik and Tribec viruses belonging to a group of Kemerovo viruses were isolated from male and female I. ricinus ticks collected from cattle.

CY - CZECHOSLOVAKIA VL - 30 SN - 0022-1732 IS - 1 N1 - LR: 20041117; JID: 2985116R; 0 (Antibodies, Viral); ppublish ER -